Clinical trials

Clinical trials, unlike observational studies, contain an intervention that determines the safety, efficiency and dosage of drugs. Clinical trials in the UK may be randomised in separate groups of participants to receive the standard of care or medicine as prescribed. These trials are generally blind, meaning that the participants, physicians and the study team are not aware of the treatment that the participant is about to receive.

These trials have four phases, but before starting Phase-I, extensive knowledge and data have to be obtained from models. The data and results collected from these models will indicate whether the drug is promising enough to combat a disease. The approved phases of these clinical trials are:

  • Phase-I: 20-200 participants
  • Phase-II: Approx. 200 participants
  • Phase-III: Thousands of international participants
  • Phase-IV: Monitored and pending approvals with an increased focus on reactions and side effects

Importance of Clinical Trials

Clinical trials are important for discovering new treatments for diseases, as well as finding ways to diagnose, detect and reduce the spread of that disease. Clinical trials in the UK can show researchers what does and does not work on humans, and cannot be tested on animals, much less humans. These trials also help doctors decide whether the side effects of a newly-developed medicine are acceptable compared to the benefits it has. Such uncertainty makes it difficult for a patient to participate in clinical trials as in rare cases, participants might be adversely affected. While clinical trials are essential, the choice to become a participant in a trial is a personal one, and may depend upon the situation.

How Clinical Trials Work

Whenever a person volunteers to participate in a clinical trial, they may get the treatment in any hospital, clinic or doctor’s office. In general, participating in a clinical trial is different from taking regular medication, as you would undergo more medical testing than you would otherwise. The purpose of the research is usually to find treatment for diseases while adhering to human rights laws and medical procedures at the same time. This combined help determines the best results and protects the patients, as well.

One of the main reasons that clinical trials are conducted is because the results can benefit scores of other patients. After the trials are carried out, and if they are successful, they result in a new medication, vaccines, or devices being manufactured for previously incurable diseases.

Remember that behind every medicine on the market, thousands of volunteers participated in clinical trials to help their community (and the world at large) discover treatments for various illnesses. It is also essential to understand that only clinical researches are not always a sure way of finding new ways of treatments. These trials also contribute to the benefits and safety of the existing therapies. For those who have participated in clinical trials in the UK, these people are considered heroes to improve health care conditions for people.

May 18, 2020
importance of Clinical Trials & How Clinical Trials Work?

Importance of Clinical Trials & How Clinical Trials Work?

Clinical trials, unlike observational studies, contain an intervention that determines the safety, efficiency and dosage of drugs. Clinical trials in the UK may be randomised in […]